A study explored the impact of mouth rinse containing ozone against the two main bacteria that produce gum disease. Also studied was its toxicity to human oral tissue cells. The researchers found that “NBW3( nano-bubble water) possesses potent bactericidal activity against representative periodontopathogenic bacteria and is not cytotoxic to cells of human oral tissues. The use of NBW3 as an adjunct to periodontal therapy would be promising.”
The first step in the treatment of periodontitis, generally includes the removal of the bacteria and the hard deposits which enables them to attach to the teeth. The second step involves the use of antiseptics and antibiotics to remove any remaining bacterial contamination and support the healing process. Antibiotic therapies have a downside, there is the need to have them ingested which can lead to the development of bacterial resistance and possibly a host reaction. The topical use of a low-cost antiseptic is the preferred option since it does not involve the ingestion of the active ingredient.
The use of active oxygen, in the form of hydrogen peroxide, to prevent and treat gum inflammation has been explored and is widely supported by research.  My experience supports these findings and we have published before that there is a unit that can produce hydrogen peroxide at home for free.